• The effect of gadolinium-based contrast-agents on automated brain atrophy measurements by FreeSurfer in patients with multiple sclerosis 

      Lie, Ingrid Anne; Kerklingh, Emma; Wesnes, Kristin; van Nederpelt, David R.; Brouwer, Iman; Torkildsen, Øivind; Myhr, Kjell-Morten; Barkhof, Frederik; Bø, Lars; Vrenken, Hugo (Journal article; Peer reviewed, 2022)
      Objective To determine whether reliable brain atrophy measures can be obtained from post-contrast 3D T1-weighted images in patients with multiple sclerosis (MS) using FreeSurfer. Methods Twenty-two patients with MS ...
    • The Effect of Smoking on Long-term Gray Matter Atrophy and Clinical Disability in Patients with Relapsing-Remitting Multiple Sclerosis 

      Lie, Ingrid Anne; Wesnes, Kristin; Kvistad, Silje S.; Brouwer, Iman; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Barkhof, Frederik; Vrenken, Hugo; Myhr, Kjell-Morten; Bø, Lars; Torkildesen, Øivind (Journal article; Peer reviewed, 2022)
      Background and Objectives The relationship between smoking, long-term brain atrophy, and clinical disability in patients with multiple sclerosis (MS) is unclear. Here, we assessed long-term effects of smoking by evaluating ...
    • Relationship between White Matter Lesions and Gray Matter Atrophy in Multiple Sclerosis 

      Lie, Ingrid Anne; Weeda, Merlin M.; Mattiesing, Rozemarijn M.; Mol, Marijke A.E.; Pouwels, Petra J.W.; Barkhof, Frederik; Torkildsen, Øivind; Bø, Lars; Myhr, Kjell-Morten; Vrenken, Hugo (Journal article; Peer reviewed, 2022)
      Background and Objectives: There is currently no consensus about the extent of gray matter (GM) atrophy that can be attributed to secondary changes after white matter (WM) lesions or the temporal and spatial relationships ...
    • Serum neurofilament as a predictor of 10-year grey matter atrophy and clinical disability in multiple sclerosis: a longitudinal study 

      Lie, Ingrid Anne; Kacar, Sezgi; Wesnes, Kristin; Brouwer, Iman; Kvistad, Silje S.; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Varhaug, Kristin Nielsen; Vedeler, Christian Alexander; Barkhof, Frederik; Teunissen, Charlotte E.; Bø, Lars; Torkildsen, Øivind Fredvik Grytten; Myhr, Kjell-Morten; Vrenken, Hugo (Journal article; Peer reviewed, 2022)
      Background The predictive value of serum neurofilament light chain (sNfL) on long-term prognosis in multiple sclerosis (MS) is still unclear. Objective Investigate the relation between sNfL levels over a 2-year ...